About 5 infants with spina bifida and about 5 infants with cleft palate could be born without these defects each year in the united states if carbamazepine were not used during pregnancy. Spina bifida is a birth defect that occurs when the spine and spinal cord don t form properly.
Spina bifida cleft spine is a neural tube defect a disorder involving incomplete development of the brain spinal cord and or their protective coverings caused by the failure of the fetus s spine to close properly during the first month of pregnancy.
Spina bifida cleft. Spina bifida is a congenital malformation in which there is something wrong with the bone in the vertebral column exposing the spinal cord which should be protected within the vertebral column. The neural tube is the embryonic structure that eventually develops into the baby s brain and spinal cord and the tissues that enclose them. In more severe cases it involves the spinal cord.
The term spina bifida means split or open spine. Spina bifida cleft spine is a birth defect affecting the spinal column. Congenital malformation means a birth defect.
The neural tube is the structure in a developing embryo that eventually becomes the baby s brain spinal cord and the tissues that enclose them. It is caused by the incomplete closing of the embryonic neural tube. This usually involves the lower lumbosacral spine.
The central nervous system includes the brain nerves and spinal cord. Spina bifida is part of a group of birth defects called neural tube defects. Spina bifida occulta is a congenital defect which occurs in the neural tube when the bony plates that form the bony spine covering the spinal cord do not form completely resulting in a defect of the spinous process spinous cleft or laminae paraspinal cleft 3 4.
Cleft palate and spina bifida. In severe cases the spinal cord protrudes through the back and may be covered by skin. Spina bifida progresses from a cleft or splitlike opening in the back part of the backbones the spinal vertebrae.
Spina bifida or cleft spine. It s a type of neural tube defect. About 40 infants with spina bifida and about 35 infants with cleft palate could be born without these defects each year in the united states if valproic acid were not used during pregnancy.
Spina bifida is a birth defect that involves the incomplete development of the spinal cord or its coverings. If you liked this article maybe you will also find interesting the following in depth articles about other rare diseases like rod cone dystrophy and gliosis related diseases and genetic alterations ventricular septal defect and renal agenesis.