Because half of all pregnancies in the united states are unplanned it is important that all women who can become pregnant take 400 mcg of folic acid daily. Women who have a history of ntds like spina bifida need to take 4000 micrograms of folic acid via prescription daily for a few months before becoming pregnant and during the first few months of pregnancy.
By contrast mills et al 4 found no protective effect of dietary folate and multivitamins plus 0 8 mg folic acid in a population based case control study in california and illinois.
Folate spina bifida. Although folic acid is not a guarantee that a woman will have a healthy pregnancy taking folic acid can help reduce a woman s risk of having a pregnancy affected by spina bifida. Women who have spina bifida a child with sb or had a pregnancy affected by sb should take 4000 mcg 4 0 mg of folic acid for one to three months before pregnancy. In pregnancy folic acid helps your unborn baby s brain skull and spinal cord develop properly to avoid development problems such as spina bifida.
Posted august 29 2017 by tammy kacev. Spina bfida folate. And it s possible that folic acid will also help reduce the risk of other birth defects including cleft lip cleft palate and some congenital heart defects.
Bower and stanley who evaluated spina bifida cases in western australia reported high dietary folate intake and multivitamin supplement use associated with a 75 risk reduction. Research has shown the lack of folic acid folate is a contributing factor in the pathogenesis of neural tube defects including spina bifida. Studies suggest if women were to consume 400 micrograms of the b vitamin folic acid before and during early pregnancy neural tube defects like spina biįda may be reduced by up to 70.
Spina bifida is part of a group of birth defects called neural tube defects. Supplementation of the mother s diet with folate can reduce the incidence of neural tube defects by about 70 and can also decrease the severity of these defects when they occur. All women of childbearing age in the united states who are capable of becoming pregnant should consume 0 4 mg of folic acid per day for the purpose of reducing their risk of having a pregnancy affected with spina bifida or other ntds.
This article summarizes the more important of these stu. Spina bifida is one of the most common disabling birth defects. Your body doesn t absorb folate as easily as it absorbs synthetic folic acid and most people don t get the recommended amount of folate through diet alone so vitamin supplements are necessary to prevent spina bifida.
This amount of folic acid is available only through prescription so high risk women must carefully plan their pregnancies. A protective effect of folate against the development of neural tube defects ntds specifically anencephaly and spina bifida is now well recognized having been established by a chain of clinical research studies over the past half century. Folate helps your body make healthy red blood cells and is a naturally occurring source in some foods such as broccoli leafy green vegetables chickpeas and kidney beans.
The term spina bifida literally means split spine spina bifida occurs when the spinal column of the fetus does not close all of the way.