Varying levels of afp can be caused by other factors including a miscalculation in fetal age or multiple babies so your doctor may order a follow up blood test for confirmation. The following prenatal tests for pregnant women detect spina bifida before babies are born.
An afp test might be part of a test called the triple screen that looks for neural tube defects and other issues.
Afp spina bifida. Having a little afp present is normal as it tends to cross the placenta and into the mother s bloodstream. Kadar afp yang tinggi dalam darah ibu hamil bisa menandakan janin berpotensi mengalami kecacatan tabung saraf seperti spina bifida. This is a simple blood test that measures how much afp has passed into the mother s bloodstream from the baby.
Test to confirm high afp levels. A positive test with a high afp suggests a birth defect like spina bifida. Usg ultrasonografi pemindaian visual pada janin melalui usg dapat membantu mendeteksi spina bifida.
But abnormally high levels of afp suggest that the baby has a neural tube defect such as spina bifida though high levels of afp don t always occur in spina bifida. A high level of afp might mean that the baby has spina bifida. Gestational age date on which the patient was the stated gestational age how gestational age was determined lmp edd us patient s weight patient s date of birth patient s race white black other and insulin dependent diabetic status.
The results are combined with the mother s age and ethnicity in order to assess the probabilities of potential genetic disorders. This test does not screen for down syndrome or trisomy 18. The following information must be provided.
In 1972 brock and sutcliffe measured afp in the amniotic fluid of 31 pregnancies with anencephaly and 6 pregnancies with spina bifida hydrocephaly or both conditions. The afp test is measuring high and low levels of alpha fetoprotein. This test screens for open spina bifida.
It is only when afp levels are extremely high will a medical provider begin to suspect that spina bifida may be a possibility. That s typically a result of 2 5 times or more than the average level of afp you d expect to see at that point in your. High levels of afp may suggest the developing baby has a neural tube defect such as spina bifida or anencephaly.
It measures levels of alpha fetoprotein afp a protein released by the baby s. The spina bifida blood test will measure the amount of alpha fetoprotein afp that is in the mother s blood. Alpha fetoprotein afp test afp is the prenatal test most commonly used to detect spina bifida.
This simple blood test is performed between 15 and 20 weeks of pregnancy. 21 all of the cases of anencephaly and most of the spina bifida cases before 30 weeks gestation demonstrated amniotic fluid afp levels that were markedly elevated during. Spina bifida is a congenital problem which means it is present before birth.
It results from the incomplete closing of the embryonic neural tube.